Human anatomical and physiological systems represent a systematic association of different types of organs arranged together in such a manner to perform complex functions for the body. Human physiology provides an exciting opportunity to understand the mechanism of each event that occurs within the body. Human organ systems maintain the homeostasis of the body by working together in a coordinated manner to support cellular processes. Several important questions on physiological concepts and anatomical perspectives remain unsolved. This textbook precisely explains the fundamental concepts of human anatomy and physiology along with different mechanisms and events occurring during a particular process. For simplicity and better understanding, this textbook is divided into 12 individual chapters. The main characteristics of this book are as follows: At the beginning of each chapter, a summary is given, describing the entire chapter. Towards the end of each chapter, a box containing additional relevant information regarding the chapter is given. At the end of each chapter, 15-20 questions are given for readers to test their understanding. This book intends to address the difficulties faced by readers while studying the chapters with simple flowcharts and diagrams based on the author’s experience during her postgraduation. Considering the interrelatedness between health and physiology, the impairment of processes, parts of processes, or any error occurring during commencement of physiological pathways results in disorders or diseases. Detailed information regarding such disorders or diseases for individual physiological systems is briefly discussed herein. This textbook offers a significant solution to the problems often encountered by students while studying and understanding human anatomy and physiology.