The latest Competency Based Medical Education Guidelines for the undergraduate students lay emphasis on 'Outcome Based Learning'. Problem based learning and Integrated teaching are innovative teaching-learning methods to enhance learning outcomes. There is scarcity of books to cater to the needs of the students and teachers. This book aims to bridge the gap between theoretical knowledge and clinical practice. Clinically relevant topics are selected and hypothetical case scenarios are designed based on learning objectives. Each case is followed by a series of questions with appropriate answers. The case presentation with question-answer format covers major pharmacological principles of the topic. This book will serve as a rich resource material in teaching, and help students to enhance critical thinking develop analytical skills imbibe ability to interpret data and diagnose and solve clinical problems. Salient Features of the Book. This book will serve as a rich resource material in teaching, and help students to enhance critical thinking develop analytical skills imbibe ability to interpret data and diagnose and solve clinical problems. It provides holistic understanding of real-life clinical situations by integrating the basic principles of pharmacology with clinical use of drugs. It includes a broader coverage of topics of pharmacology having clinical relevance, and each topic has been dealt in-depth to strengthen the concepts and makes learning more effective. Hypothetical case scenarios are designed and the principles of pharmacology in drug use is discussed in a question-answer format progressing stepwise from the basics to higher learning levels of each topic. The book will be beneficial for different categories of learners—poor, medium and advanced. There is greater emphasis on 'rationale type' questions to improve reasoning and analytical skills of the learner. Schematic diagrams, flowcharts and tables have been included wherever necessa.